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pentobarbital will lessen the extent or effect of exemestane by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. For sufferers receiving exemestane with a strong CYP3A4 inducer the recommended dose of exemestane is 50 mg every day following a meal.Soon after halting a CYP3A4 inducer, as the effects from the inducer decrea